Anybody Out There? is the title track from Burlap to Cashmere's 1998 album of the same name.
Its lyrics are very deep and introspective. They speak of feeling alone and abandoned, and a longing for deliverance. Job longed for a mediator who would end his suffering (Job 9:32-35). The authors of the Psalms felt lonely and forsaken (Psalm 13:1-6, 22, 27:10, 34:1-9, 142). Similarly, the book of Lamentations speaks to the feeling of despair and being estranged from God, with almost no hope of reconciliation.
God's ears are not deaf to the cries of His people for deliverance. Again, the song's lyrics refer to Jesus calling home a lost sinner. This person was "deaf and dumb," but in Jesus, found the answers to the questions of who they are and what their life is for.
On the cross Jesus also felt the pain of human separation from God (Matthew 27:46). A holy God cannot bear to the in the presence of sin, so by his death upon the cross, burial, and resurrection, Jesus took the penalty for sin upon himself, making it possible for humanity to be reconciled to God (2 Corinthians 5:21), and to have a relationship with Him, but only for those who repent and realize their need for forgiveness.
Anybody Out There rightly points to Jesus as the hope of the world, and as the only one who can satisfy the deepest longings of the human heart, answering the questions of life and its deeper purpose. Sadly, it seems that some peoples' hearts are so hardened against God that they'd ignore Him even if He whispered directly into their ears. On the outside those who live with no regard for God, may often appear to be happy and untroubled by the cares of this life, but little do they know that they are dead or dying inside.